ACG 150

The Biomedical Science Research Team (BMSR) is currently engaged in research activities from different areas such as chemical biology, neuroscience, pharmacology, structural biology and molecular biophysics, bioinformatics, big data analytics, artificial intelligence, health, and healthcare, environmental health, sustainability, and the area of medical psychology/behavioral medicine.

Applications of our research span from:

  • Medicine & Healthcare
  • Precision medicine
  • Cancer research
  • Genetic and rare diseases
  • Neurodegenerative diseases
  • Synthesis and biological evaluation of chemicals
  • Bioinformatics and Artificial Intelligence (AI) in medicine, health & healthcare
  • Sustainability, STEM and biomedical education
  • To medical psychology

Our overarching aim is to bridge internal and external research collaborations in biomedical science, promote research excellence and innovation, and ultimately improve the health and well-being of our society at large.

BMSR Research Team Members

Currently, the BMSR team 5 members:

Dr. Paraskevi Papadopoulou (Team Leader)
Professor, Biophysicist, Cell Biologist
Biomedical Sciences & Environmental Studies Programs
Department of Science and Mathematics &
Biomedical Sciences Research (BMSR) Team Leader @ Research, Technology and Innovation Network (RTIN), Deree-The American College of Greece

Dr. Georgia Kythreoti
Assistant Professor, Chemical Biology
Department of Science and Mathematics
School of Liberal Arts and Sciences

Dr. Alexia Victoria Polissidis
Assistant Professor of Pharmacology
Biomedical Sciences Program
Department of Science and Mathematics

Dr.  Athena Stefanatou
DEREE College-School of Graduate & Professional Education
The American College of Greece

Dr. Marina Sagnou
Medicinal Chemistry
Researcher B’
Institute of Biosciences and Applications
NCSR “Demokritos”
PT Chemistry instructor,
Department of Science and Mathematics

Mission

To conduct high-caliber and high-impact research in select BMSR areas; to attract funding through proposal writing; to attract and retain students to do research in Biomedical Sciences; to collaborate with other research teams on inter-disciplinary topics and applications related to Biomedical Science; to foster collaborations with academia and industry.

Vision

To perform world-class research in Biomedical Science and its applications.

Current Research Funding and Grants

The BMSR Research Team is actively pursuing research grants including the European Commission’s HORIZON programs, EU COST programs, and HFRI, in collaboration with external partners. We are always open to new collaborations at the global level, so please contact us if you are interested.

2024: ACG 150 funding for research for testing some compounds in vitro for potential neuroprotective effects.

2024: ACG 150 funding for research/curriculum, project “Natural Products R&D Facility,” ACG 150 initiatives for supporting research and/or curriculum development.

2022-today: ACG 150 funding for research/curriculum, project “Natural Product Analogues as Antibacterial Agents”, ACG 150 initiatives for supporting research and/or curriculum development.

2022: ACG-RC research project funded under the Erasmus+ Programme of the European Commission. Title: Engaging SDGs for Transformative Education and Enhanced Sustainability in Universities (ERASMUS+) SDG4U, Project Number: KA220-HED-49754B7A https://www.sdg4uproject.eu/ | https://sdg4u.uoa.gr/

Current Collaborations

The BMSR team works with a large pool of collaborators on a number of joint projects and publications, including visits, scientific collaborations, technology consulting, infrastructure sharing, etc. Our collaborating partners include national academic institutions such as the National and Kapodistrian University of Athens, Aristotle University of Thessaloniki, the University of Ioannina, the Agricultural University of Athens, National Technical University of Athens, and the Athens University of Economics and Business. We also collaborate with several research institutes, such as the National Center for Scientific Research “Demokritos,” the Athena Research Center, The Biomedical Research Foundation of the Academy of Athens (BRFAA) and the Biomedical Sciences Research Center Alexander Fleming. Collaborations with foreign universities include Columbia University, University of Iceland and Queen's University Belfast. On the industrial front we collaborate with Pharmaceutical companies, diagnostic centers and hospitals and we are members of the Hellenic BioCluster (HBio).

Collaboration with the National Center for Scientific Research “Demokritos” and the Biomedical Research Foundation Academy of Athens

The BMSR Research Team currently is actively pursuing research on topics related to:

  • Synthesis and biological evaluation of novel small molecules as potential autophagy inducers and anti-Parkinson agents
  • Identification of isolates with anti-cancer, anti-oxidant, anti-inflammatory and neuroprotective effects
  • Projects related to the synthesis and evaluation of molecules with anti-bacterial (photodynamic therapy, resistance), anti-infective and anti-malarial activity.
  • Projects related to the identification of novel anosmia-inducing compounds for environmentally friendly mosquito vector control and structural determinants of ORco ligands antagonizing odorant receptor function.
  • Projects related to the development of hydrophilic antimicrobial coatings from silica-dendritic polymer-antibiotic Nanoparticle Composite Xerogels, for the preparation of materials intended for medical uses.

Research collaboration with Deree-ACG faculty and other external collaborators

The BMSR Research Team currently is actively pursuing research on topics related to:

  • Medicine, precision medicine, cancer research, genetic and rare diseases, bioinformatics and Artificial Intelligence (AI) as it applies to medicine, health, healthcare, sustainability, STEM and, biomedical education.
  • Crisis intervention, chronic disease, anxiety and depression in health and illness, developmental psychopathology, development of counseling and psychotherapy protocols in Health Care.

Collaboration with Theoharis C. Theoharides, BA, MS, MPhil, PhD, MD, FAAAAI

Collaboration with Theoharis C. Theoharides Director, Center of Excellence for Neuroinflammation Research, Nova Southeastern University, Professor, Institute for Neuro-Immune Medicine

Chief Consultant and Chair
of the Health Sciences Research and Education Advisory Board, Deree, ACG.

The BMSR Research Team is actively pursuing research on:

  • Antioxidants and anti-inflammatory compounds such as polyphenols
  • Their impact on cognitive health
  • Anti-inflammatory mechanisms
  • Neuroprotective effects

Facilities-Laboratory Infrastructure-Resources

Natural Products R&D Facility

Natural products R&D facility engages in research towards the identification of novel naturally occurring compounds for potential pharmaceutical, cosmetic, or nutritional applications.

Science Labs and Research Spaces at Deree

The BMSR team has at its disposal the following lab resources and access to their research spaces: The fully renovated Deree labs (Biology lab, Chemistry & Cell and Molecular Lab, and the Physical Sciences lab) which feature state-of-the-art infrastructure for basic science research and training. The Natural Products R&D Facility (see link to NPF) comprises state-of-the-art equipment supporting such an interdisciplinary approach. Namely, extraction, separation, and analysis equipment, such as High Pressure Liquid Chromatography (HPLC) and has access to UV/Vis spectrophotometry, Fluorescent Microscopy, Fluorescence and Luminescence high-throughput screening, bacterial and cell culture growth and maintenance equipment and various Molecular Biology equipment. We plan to/are currently optimizing isolation methods, etc., and look forward to working with academic and private research partners at the national and international level.

The Chemistry & Cell and Molecular Lab

The lab is equipped with all the necessary equipment to serve Cell and Molecular Biology, General and Organic Chemistry. It includes vacuum and gas installation (to all fume hoods and also in all 6 student working areas). Additional fume hoods were acquired to accommodate the needs for chemistry courses as well as an HPLC system, analytical balances, a rotary evaporator, melting point apparatus, and other materials like bomb calorimeters, general purpose glassware. Cell Molecular Biology courses are served with a Biosafety cabinet Class II two thermocyclers for PCR, microplate spectrophotometer, refrigerated centrifuge, shaking incubator, tissue homogenizer additional electrophoresis systems (horizontal and vertical), gel imaging system and an autoclave. An individual room was created to accommodate a -80°C freezer, liquid nitrogen tanks, and additional refrigerators. The lab is also used by researchers when not occupied by students.

The Biology Lab

The biology lab is designed as a laboratory space for educational and also research purposes. It is equipped with an Anatomy Table, light and stereo microscopes, rich collection of slides, plastomounts and models, dissection tools, gas and vacuum installation to the fume hoods, a cell-culture room with a Biosafety Cabinet Class II, germicidal UV light, a CO2 incubator and an inverted fluorescence microscope. A separate space was created to be used as research area, containing all basic equipment.

The Physical Sciences Lab

The Physical Sciences Lab hosts Physics courses along with all Earth and Environmental Science courses. The lab has been equipped with 3 big benches with working areas for 6 groups of 4 students, PC stations, a fume hood and a chemical cabinet for safe storage. The acquired equipment support various experiments on mechanics, waves and acoustics and thermodynamics, on electromagnetism, optics and modern Physics.

Select Publications